Designing a semantically rich visual interface for cultural digital libraries using the UNEsCO multilingual thesaurus

This paper reports on the design of a visual user interface for the UNESCO digital portal. The interface makes use of the UNESCO multilingual thesaurus to provide visualized views of terms and their relationships and the way in which spaces associated with the thesaurus, the query and the results can be integrated into a single user interface

Designing a Semantically Rich Visual Iinterface for Cultural Digital Libraries Using the UNESCO Multilingual Thesaurus

This paper reports on the design of a visual user interface for the UNESCO digital portal. The interface makes use of the UNESCO multilingual thesaurus to provide visualized views of terms and their relationships and the way in which spaces associated with the thesaurus, the query and the results can be integrated into a single user interface.\u

A Short History and Demonstration of the Dynamic Table of Contexts

This paper presents a brief account of the form and function of the “table of contents” to establish a theoretical framework for understanding the form and function of this common element of book architecture with the aim of informing the development of a dynamic table of contexts for books and reading in the digital medium. This paper will thus theorize the relationship between textual studies and interface design in INKE, a project for Implementing New Knowledge Environments

Evidence for the Role of B Cells and Immunoglobulins in the Pathogenesis of Multiple Sclerosis

The pathogenesis of multiple sclerosis (MS) remains elusive. Recent reports advocate greater involvement of B cells and immunoglobulins in the initiation and propagation of MS lesions at different stages of their ontogeny. The key role of B cells and immunoglobulins in pathogenesis was initially identified by studies in which patients whose fulminant attacks of demyelination did not respond to steroids experienced remarkable functional improvement following plasma exchange. The positive response to Rituximab in Phase II clinical trials of relapsing-remitting MS confirms the role of B cells. The critical question is how B cells contribute to MS. In this paper, we discuss both the deleterious and the beneficial roles of B cells and immunoglobulins in MS lesions. We provide alternative hypotheses to explain both damaging and protective antibody responses

Drilling for Papers in INKE

In this article, we discuss the first year research plan for the INKE interface design team, which focuses on a prototype for chaining. Interpretable as a subclass of Unsworths scholarly primitive of discovering, chaining is the process of beginning with an exemplary article, then finding the articles that it cites, the articles they cite, and so on until the reader begins to get a feel for the terrain. The chaining strategy is of particular utility for scholars working in new areas, either through doing background work for interdisciplinary interests or else by pursuing a subtopic in a domain that generates a paper storm of publications every year. In our prototype project, we plan to produce a system that accepts a seed article, tunnels through a number of levels of citation, and generates a summary report listing the most frequent authors and articles. One of the innovative features of this prototype is its use of the experimental oil and water interface effect, which uses text animation to provide the user with a sense of the underlying process

The Beginning, The Middle, and The End: New Tools for the Scholarly Edition

This article discusses a set of prototypes currently being designed and created by the Interface Design team of the Implementing New Knowledge Environments (INKE) project. These prototypes attempt to supplement the user experience in reading digital scholarly editions, by supporting a set of tasks that are straightforward in a digital environment but in a print edition would be sufficiently more difficult as to be prohibitive. We therefore offer these experimental prototypes as a collection of new affordances for the scholarly edition, although they may reasonably be extended, with some variation, to other kinds of digital text

The Beginning, The Middle, and The End: New Tools for the Scholarly Edition

This article discusses a set of prototypes currently being designed and created by the Interface Design team of the Implementing New Knowledge Environments (INKE) project. These prototypes attempt to supplement the user experience in reading digital scholarly editions, by supporting a set of tasks that are straightforward in a digital environment but in a print edition would be sufficiently more difficult as to be prohibitive. We therefore offer these experimental prototypes as a collection of new affordances for the scholarly edition, although they may reasonably be extended, with some variation, to other kinds of digital text

Fall Classification by Machine Learning Using Mobile Phones

Fall prevention is a critical component of health care; falls are a common source of injury in the elderly and are associated with significant levels of mortality and morbidity. Automatically detecting falls can allow rapid response to potential emergencies; in addition, knowing the cause or manner of a fall can be beneficial for prevention studies or a more tailored emergency response. The purpose of this study is to demonstrate techniques to not only reliably detect a fall but also to automatically classify the type. We asked 15 subjects to simulate four different types of falls–left and right lateral, forward trips, and backward slips–while wearing mobile phones and previously validated, dedicated accelerometers. Nine subjects also wore the devices for ten days, to provide data for comparison with the simulated falls. We applied five machine learning classifiers to a large time-series feature set to detect falls. Support vector machines and regularized logistic regression were able to identify a fall with 98% accuracy and classify the type of fall with 99% accuracy. This work demonstrates how current machine learning approaches can simplify data collection for prevention in fall-related research as well as improve rapid response to potential injuries due to falls

The association of functional status with mortality and dialysis modality change : results from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS)

BACKGROUND: Little is known about the prevalence of functional impairment in peritoneal dialysis (PD) patients, its variation by country, and its association with mortality or transfer to hemodialysis. METHODS: A prospective cohort study was conducted in PD patients from 7 countries in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) (2014 - 2017). Functional status (FS) was assessed by combining self-reports of 8 instrumental and 5 basic activities of daily living, using the Lawton-Brody and the Katz questionnaires. Summary FS scores, ranging from 1.25 (most dependent) to 13 (independent), were based on the patient's ability to perform each activity with or without assistance. Logistic regression was used to estimate the odds ratio (OR; 95% confidence interval [CI]) of a FS score < 11 comparing each country with the United States (US). Cox regression was used to estimate the hazard ratio (HR; 95% CI) for the effect of a low FS score on mortality and transfer to hemodialysis, adjusting for case mix. RESULTS: Of 2,593 patients with complete data on FS, 48% were fully independent (FS = 13), 32% had a FS score 11 to < 13, 14% had a FS score 8 to < 11, and 6% had a FS score < 8. Relative to the US, low FS scores (< 11; more dependent) were more frequent in Thailand (OR = 10.48, 5.90 - 18.60) and the United Kingdom (UK) (OR = 3.29, 1.77 - 6.08), but similar in other PDOPPS countries. The FS score was inversely and monotonically associated with mortality but not with transfer to hemodialysis; the HR, comparing a FS score < 8 vs 13, was 4.01 (2.44 - 6.61) for mortality and 0.91 (0.58 - 1.43) for transfer to hemodialysis. CONCLUSION: Regional differences in FS scores observed across PDOPPS countries may have been partly due to differences in regional patient selection for PD. Functional impairment was associated with mortality but not with permanent transfer to hemodialysis